作者
Josiah Ochieng, Gladys N Nangami, Olugbemiga Ogunkua, Isabelle R Miousse, Igor Koturbash, Valerie Odero-Marah, Lisa J McCawley, Pratima Nangia-Makker, Nuzhat Ahmed, Yunus Luqmani, Zhenbang Chen, Silvana Papagerakis, Gregory T Wolf, Chenfang Dong, Binhua P Zhou, Dustin G Brown, Anna Maria Colacci, Roslida A Hamid, Chiara Mondello, Jayadev Raju, Elizabeth P Ryan, Jordan Woodrick, A Ivana Scovassi, Neetu Singh, Monica Vaccari, Rabindra Roy, Stefano Forte, Lorenzo Memeo, Hosni K Salem, Amedeo Amedei, Rabeah Al-Temaimi, Fahd Al-Mulla, William H Bisson, Sakina E Eltom
发表日期
2015/6/1
来源
Carcinogenesis
卷号
36
期号
Suppl_1
页码范围
S128-S159
出版商
Oxford University Press
简介
The purpose of this review is to stimulate new ideas regarding low-dose environmental mixtures and carcinogens and their potential to promote invasion and metastasis. Whereas a number of chapters in this review are devoted to the role of low-dose environmental mixtures and carcinogens in the promotion of invasion and metastasis in specific tumors such as breast and prostate, the overarching theme is the role of low-dose carcinogens in the progression of cancer stem cells. It is becoming clearer that cancer stem cells in a tumor are the ones that assume invasive properties and colonize distant organs. Therefore, low-dose contaminants that trigger epithelial–mesenchymal transition, for example, in these cells are of particular interest in this review. This we hope will lead to the collaboration between scientists who have dedicated their professional life to the study of carcinogens and those whose interests …
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J Ochieng, GN Nangami, O Ogunkua, IR Miousse… - Carcinogenesis, 2015