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To prospectively compare the capability for bone metastasis assessment of whole‐body diffusion‐weighted imaging (DWI), magnetic resonance imaging (MRI) without and with DWI, [¹⁸F] fluoro‐2‐D‐glucose positron emission tomography with computed tomography (FDG‐PET/CT) and bone scintigraphy in non‐small cell carcinoma (NSCLC) patients.

In all, 115 consecutive NSCLC patients (66 men, 49 women; mean age 72 years) prospectively underwent whole‐body MRI, PET/CT, and bone scintigraphy before treatment. For each method, probability of metastasis was independently assessed by using a 5‐point visual scoring system on a per‐site basis. Receiver operating characteristic (ROC)‐based positive tests were used to determine the practical threshold value for each method on a per‐site basis. Sensitivities, specificities, and accuracies were then compared on a per …