作者
Simon Ducharme, Annemiek Dols, Robert Laforce, Emma Devenney, Fiona Kumfor, Jan Van Den Stock, Caroline Dallaire-Théroux, Harro Seelaar, Flora Gossink, Everard Vijverberg, Edward Huey, Mathieu Vandenbulcke, Mario Masellis, Calvin Trieu, Chiadi Onyike, Paulo Caramelli, Leonardo Cruz De Souza, Alexander Santillo, Maria Landqvist Waldö, Ramon Landin-Romero, Olivier Piguet, Wendy Kelso, Dhamidhu Eratne, Dennis Velakoulis, Manabu Ikeda, David Perry, Peter Pressman, Bradley Boeve, Rik Vandenberghe, Mario Mendez, Carole Azuar, Richard Levy, Isabelle Le Ber, Sandra Baez, Alan Lerner, Ratnavalli Ellajosyula, Florence Pasquier, Daniela Galimberti, Elio Scarpini, John Van Swieten, Michael Hornberger, Howard Rosen, John Hodges, Janine Diehl-Schmid, Yolande Pijnenburg
发表日期
2020/6
来源
Brain
卷号
143
期号
6
页码范围
1632-1650
出版商
Oxford University Press
简介
The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-onset dementia. The diagnosis of bvFTD remains challenging because of the limited accuracy of neuroimaging in the early disease stages and the absence of molecular biomarkers, and therefore relies predominantly on clinical assessment. BvFTD shows significant symptomatic overlap with non-degenerative primary psychiatric disorders including major depressive disorder, bipolar disorder, schizophrenia, obsessive-compulsive disorder, autism spectrum disorders and even personality disorders. To date, ∼50% of patients with bvFTD receive a prior psychiatric diagnosis, and average diagnostic delay is up to 5–6 years from symptom onset. It is also not uncommon for patients with primary psychiatric disorders to be wrongly diagnosed with bvFTD. The Neuropsychiatric International Consortium for Frontotemporal …
学术搜索中的文章
S Ducharme, A Dols, R Laforce, E Devenney, F Kumfor… - Brain, 2020