作者
Borja G Cosio, Joan B Soriano, Jose Luis López-Campos, Myriam Calle-Rubio, Juan José Soler-Cataluna, Juan P de-Torres, Jose M Marín, Cristina Martínez-Gonzalez, Pilar de Lucas, Isabel Mir, Germán Peces-Barba, Nuria Feu-Collado, Ingrid Solanes, Inmaculada Alfageme, Ciro Casanova, José Calvo Bonachera, Celia Lacárcel Bautista, Adolfo Domenech, Rosirys Guzmán, Rosa Irigaray, Meritxell López Zamora, Angel Ríos, Rocío Córdova, Carlos Cabrera López, Alejandro Sánchez Acosta, Juan Abreu González, Ramón Agüero Balbin, Eva Balcells, Elena Miguel Campos, Alicia Marin, Antonia Llunel Casanova, Amalia Moreno, Francisca Lourdes Márquez Pérez, Juan Antonio Riesco Miranda, Julia Tabara Rodríguez, Rafael Golpe Gómez, Javier de Miguel Díez, Francisco García Río, Salvador Díaz Lobato, Juan Bautista Galdiz Iturri, Margarita Marín Royo, Alfredo de Diego Damia
发表日期
2016/1/1
期刊
Chest
卷号
149
期号
1
页码范围
45-52
出版商
Elsevier
简介
Background
Asthma-COPD overlap syndrome (ACOS) has been recently described by international guidelines. A stepwise approach to diagnosis using usual features of both diseases is recommended although its clinical application is difficult.
Methods
To identify patients with ACOS, a cohort of well-characterized patients with COPD and up to 1 year of follow-up was analyzed. We evaluated the presence of specific characteristics associated with asthma in this COPD cohort, divided into major criteria (bronchodilator test > 400 mL and 15% and past medical history of asthma) and minor criteria (blood eosinophils > 5%, IgE > 100 IU/mL, or two separate bronchodilator tests > 200 mL and 12%). We defined ACOS by the presence of one major criterion or two minor criteria. Baseline characteristics, health status (COPD Assessment Test [CAT]), BMI, airflow obstruction, dyspnea, and exercise capacity (BODE) index, rate …
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BG Cosio, JB Soriano, JL López-Campos… - Chest, 2016