作者
Sang Hyun Joo, Joongyub Lee, David Hutchinson, Yeong Wook Song
发表日期
2019/1/1
期刊
BMJ open
卷号
9
期号
1
页码范围
e023233
出版商
British Medical Journal Publishing Group
简介
Objectives
It has been suggested that exposure to heavy metal cadmium (Cd) may contribute to a high risk of developing rheumatoid arthritis (RA). This study was to investigate the association of RA prevalence and serum concentrations of Cd and other heavy metals through large survey data analysis.
Design
A retrospective cross-sectional survey study.
Setting
Large population survey in Korea.
Participants
53 829 subjects participated in Korean National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2013.
Interventions
Heavy metals were measured in different time periods of the survey programme which resulted in three different data sets for analysis: Cd, mercury (Hg) and lead (Pb) from 2008 to 2012 survey; serum manganese (Mn) and urine arsenic (As) from 2008 to 2009 survey; and serum zinc (Zn) from 2010 survey. RA prevalence and its associations with serum heavy metals were …
学术搜索中的文章
SH Joo, J Lee, D Hutchinson, YW Song - BMJ open, 2019