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Purpose: This study investigated the effect of in vitro accelerated aging reproduced with thermocycling on the bond strength of three commercially available permanent denture soft liners (PermaSoft, Dentuflex, Ufi‐gel) with one heat‐polymerized polymethyl methacrylate resin denture base (QC‐20) by tensile test.

Material and Methods: Ten specimens were prepared for control and test groups of each material for a total of 60 specimens. All controls were stored in water (37°C) for 24 hours before testing. All test groups received 3000 thermal cycles consisting of 1 minute at 5°C and 1 minute at 65°C. All specimens were submitted to a tensile test using a universal testing machine at a crosshead speed of 5 mm/min. Results were statistically analyzed (ANOVA, p≤ 0.05, Tukey's post‐hoc test).

Results: The mean bond strength of control specimens was (MPa): 0.32 (Ufi‐gel), 0.49 (PermaSoft), and 1.19 (Dentuflex …