作者
Amandine Coum, Lobna Ouldamer, Fanny Noury, Laurent Barantin, Aymeric Saint-Hilaire, Anne Vilde, Philippe Bougnoux, Giulio Gambarota
发表日期
2016/2
期刊
Magnetic Resonance Materials in Physics, Biology and Medicine
卷号
29
页码范围
1-4
出版商
Springer Berlin Heidelberg
简介
Objective
To evaluate the feasibility of in vivo measurement of the fatty acid (FA) composition of breast adipose tissue by MRS on a clinical platform.
Material and methods
MRS experiments were performed at 3 T, using a STEAM sequence, on 25 patients diagnosed with breast cancer. MR spectra, acquired on healthy breast tissue, were analysed with the LCModel.
Results
The measured values of the saturated fatty acid (SFA), mono-unsaturated fatty acid (MUFA) and poly-unsaturated fatty acid (PUFA) fractions were 23.8 ± 7.1 %, 55.4 ± 6.8 % and 20.8 ± 4.4 %, respectively. The values of SFA, MUFA and PUFA observed in the current study are in the same range as those found in two previous studies performed at 7 T.
Conclusion
The results of the current study show that it is possible to …
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