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The purpose of the present study was to design a model for assuring the quality of an entrepreneurial university. This qualitative research made use of interview in order to collect the required data. The statistical population of the study included the professors and faculty members specialized in the field of academic entrepreneurship. Having used purposeful sampling, some in-depth interviews were conducted with 23 subjects in order to achieve theoretical saturation. After collecting the concerned data, the process of refining, re-reading, categorizing and presenting the findings was initiated through qualitative the content-analysis technique. The qualitative research evaluation criteria, including trustworthability (equivalent to internal validity in quantitative research), transformability (equivalent to external validity in quantitative research), dependability (equivalent to reliability) and confirmability (equivalent to objectivity), were evaluated and, accordingly, the validity and reliability of the research were confirmed. Therefore, a seven-element (18 items) model, composed of leadership, entrepreneurial organizational structure and culture, financial, human, financial and infrastructural resources, entrepreneurial training, supporting entrepreneurship and commercialization, domestic, national and international partnership and cooperation, quality evaluation system and contextual factors, was designed that should be considered in order to ensure the quality of an entrepreneurial university.