作者
Othman Bin Alamer, Ali S Haider, Maryam Haider, Navraj S Sagoo, Faith C Robertson, Eliel N Arrey, Salah G Aoun, Kenny Yu, Aaron A Cohen-Gadol, Tarek Y El Ahmadieh
发表日期
2021/6
来源
Journal of Neuro-oncology
卷号
153
期号
2
页码范围
183-202
出版商
Springer US
简介
Purpose
We aim to systematically review and summarize the demographics, clinical features, management strategies, and clinical outcomes of primary and radiation-induced skull-base osteosarcoma (SBO).
Methods
PubMed, Scopus, and Cochrane databases were used to identify relevant articles. Papers including SBO cases and sufficient clinical outcome data were included. A comprehensive clinical characteristic review and survival analysis were also conducted.
Results
Forty-one studies describing 67 patients were included. The median age was 31 years (male = 59.7%). The middle skull-base was most commonly involved (52.7%), followed by anterior (34.5%) and posterior (12.7%) skull-base. Headache (27%), exophthalmos (18%), and diplopia (10%) were common presenting symptoms. Sixty-eight percent of patients had primary SBO, while 25% had radiation-induced SBO. Surgery was the main …
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O Bin Alamer, AS Haider, M Haider, NS Sagoo… - Journal of Neuro-oncology, 2021