作者
Paolo Palmisciano, Christian Ogasawara, Chibueze D Nwagwu, Othman Bin Alamer, Aditya D Gupta, Alexandra M Giantini-Larsen, Gianluca Scalia, Kenny Yu, Giuseppe E Umana, Aaron A Cohen-Gadol, Tarek Y El Ahmadieh, Ali S Haider
发表日期
2022/3/1
来源
World neurosurgery
卷号
159
页码范围
156-167. e2
出版商
Elsevier
简介
Background
Pineal region metastases are rare but often cause severe neurologic deficits. Surgical resection and chemoradiotherapy can provide therapeutic benefit. We investigated the literature to analyze clinical characteristics, management strategies, and survival of adult patients with pineal region metastases.
Methods
PubMed, Embase, Scopus, and Cochrane were searched following the PRISMA guidelines, including studies reporting clinical outcomes of patients with pineal region metastases. Clinical presentation, management, and survival were reviewed.
Results
We included 31 studies comprising 47 patients. Lung cancer (29.8%) and carcinomas of unknown origin (14.9%) were the most frequent primary tumors. In 48.9% of patients, symptomatic pineal metastases preceded primary tumor diagnosis. Headache (67.4%) and confusion (46.5%) were the most common symptoms. Parinaud syndrome (46.5 …
学术搜索中的文章
P Palmisciano, C Ogasawara, CD Nwagwu, OB Alamer… - World neurosurgery, 2022