作者
SA Sadiq, SA Vernon
发表日期
1996/6/1
期刊
British journal of ophthalmology
卷号
80
期号
6
页码范围
532-535
出版商
BMJ Publishing Group Ltd.
简介
AIMS
To assess whether timolol drops lower a raised intraocular pressure (IOP) when given sublingually. This route of administration would be useful for glaucoma patients who are unable to instil their own drops--for example, because of stroke, poor vision, arthritis, poor coordination, or blepharospasm. METHODS
A placebo controlled randomised, double masked, crossover study was undertaken in the glaucoma clinic of a large teaching hospital. Twelve patients with ocular hypertension with IOPs over 21 mm Hg, normal optic discs, and full visual fields were examined by Humphrey perimetry. Single dose units of timolol maleate 0.5% drops and normal saline drops were given by instillation in one eye or sublingually. The IOP of both eyes, pulse rate, and blood pressure were all measured before and after each type of drop and route of administration. RESULTS
Two hours after instillation of timolol in one eye, the …引用总数
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SA Sadiq, SA Vernon - British journal of ophthalmology, 1996