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Recently, radiation therapy with protons has received much attention. In 2020, nearly 250,000 patients in 110 centers around the world preferred radiation therapy with protons for treatment. One of them, proton-based stereotactic radiosurgery, is a treatment option after surgical interventions in Arteriovenous Malformation (AVM). The main goal of this research is to compute the amount of linear energy transfer (LET) delivered to the target because the highly preferred liquid embolic agents weaken the proton beam. LET, recoils, lateral straggle and crystalline vanacies accumulated by three different embolization materials: Ethylene vinyl alcohol (On), Cyanoacrylate (Ca) and polyvinyl alcohol (Pa) were analysed with an aim to calculate the ionization, rebound, phonon and lateral straggle of the brain at different depths for a 2 cm diameter AVM using Monte Carlo-based simulation. The obtained data were evaluated and …