作者
M-Ali H Al-Akhras, Khaled Aljarrah, Hasan Al-Khateeb, Adnan Jaradat, Abdelkarim Al-Omari, Amjad Al-Nasser, Majed M Masadeh, Amr Amin, Alaaeldin Hamza, Karima Mohammed, Mohammad Al Olama, Sayel Daoud
发表日期
2012/12/1
期刊
Electromagnetic Biology and Medicine
卷号
31
期号
4
页码范围
299-309
出版商
Taylor & Francis
简介
Cichorium Pumilum (chicory) is could be a promising cancer treatment in which a photosensitizing drug concentrates in benign tumor cells and activated by quanta at certain wavelength. Such activated extracts could lead to cell death and tumor ablation. Previous studies have shown that Cichorium Pumilum (chicory) contains photosensitive compounds such as cichoriin, anthocyanins, lactucin, and Lactucopicrin. In the present study, the protective effect of sun light-activated Cichorium against the dimethylbenz[a]anthracene (DMBA) induced benign breast tumors to female Sprague-Dawley rats was investigated. Chicory's extract has significantly increase P.carbonyl (PC) and malondialdehyde (MDA) and decreases the hepatic levels of total antioxidant capacity (TAC) and superoxide dismutase (SOD) in benign breast tumors-induced group compared to control. It also significantly decrease the number of estrogen …
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