作者
Lei Huang, Karthik Nagapudi, Robert P. Apkarian, Elliot L Chaikof
发表日期
2001/1/1
期刊
Journal of biomaterials science, Polymer edition
卷号
12
期号
9
页码范围
979-993
出版商
Taylor & Francis Group
简介
Type I collagen-PEO fibers and non-woven fiber networks were produced by the electrospinning of a weak acid solution of purified collagen at ambient temperature and pressure. As determined by high-resolution SEM and TEM, fiber morphology was influenced by solution viscosity, conductivity, and flow rate. Uniform fibers with a diameter range of 100-150 nm were produced from a 2-wt% solution of collagen-PEO at a flow rate of 100 μl min-1. Ultimate tensile strength and elastic modulus of the resulting non-woven fabrics was dependent upon the chosen weight ratio of the collagen-PEO blend. 1H NMR dipolar magnetization transfer analysis suggested that the superior mechanical properties, observed for collagen-PEO blends of weight ratio 1 : 1, were due to the maximization of intermolecular interactions between the PEO and collagen components. The process outlined herein provides a …
引用总数
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学术搜索中的文章
L Huang, K Nagapudi, R P. Apkarian, EL Chaikof - Journal of biomaterials science, Polymer edition, 2001