作者
Sigurdur Yngvi Kristinsson, Ola Landgren, Paul W Dickman, Asa Rangert Derolf, Magnus Bjorkholm
发表日期
2007/5/20
期刊
Journal of clinical oncology
卷号
25
期号
15
页码范围
1993-1999
出版商
American Society of Clinical Oncology
简介
Purpose
To define patterns of survival among all multiple myeloma (MM) patients diagnosed in Sweden during a 30-year period.
Patients and Methods
A total of 14,381 MM patients (7,643 males; 6,738 females) were diagnosed in Sweden from 1973 to 2003 (median age, 69.9 years; range 19 to 101 years). Patients were categorized into six age categories and four calendar periods (1973 to 1979, 1980 to 1986, 1987 to 1993, and 1994 to 2003). We computed relative survival ratios (RSRs) as measures of patient survival.
Results
One-year survival improved (P < .001) over time in all age groups and RSRs were 0.73, 0.78, 0.80, and 0.82 for the four calendar periods; however, improvement in 5-year (P < .001) and 10-year (P < .001) RSR was restricted to patients younger than 70 years and younger than 60 years, respectively. For the first time, in analyses restricted to MM …
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