作者
Nirupama Putcha, Ashraf Fawzy, Gabriel G Paul, Allison A Lambert, Kevin J Psoter, Venkataramana K Sidhaye, John Woo, J Michael Wells, Wassim W Labaki, Claire M Doerschuk, Richard E Kanner, MeiLan K Han, Carlos Martinez, Laura M Paulin, Fernando J Martinez, Robert A Wise, Wanda K O’Neal, R Graham Barr, Nadia N Hansel
发表日期
2018/6
期刊
Annals of the American Thoracic Society
卷号
15
期号
6
页码范围
710-717
出版商
American Thoracic Society
简介
Rationale: Chronic obstructive pulmonary disease (COPD) is a common cause of morbidity and associated with a significant burden of comorbidities. Although anemia is associated with adverse outcomes in COPD, its contribution to outcomes in individuals with other comorbid chronic diseases is not well understood.
Objectives: This study examines the association of anemia with outcomes in a large, well-characterized COPD cohort, and attempts to understand the contribution of anemia to outcomes and phenotypes in individuals with other comorbidities.
Methods: Participants with COPD from SPIROMICS (the Subpopulations and Intermediate Outcome Measures in COPD Study) were analyzed in adjusted models to determine the associations of normocytic anemia with clinical outcomes, computed tomographic measures, and biomarkers. Analysis was additionally performed to understand the independence and …
学术搜索中的文章
N Putcha, A Fawzy, GG Paul, AA Lambert, KJ Psoter… - Annals of the American Thoracic Society, 2018