作者
Robert M Burkes, Amanda J Gassett, Agathe S Ceppe, Wayne Anderson, Wanda K O’Neal, Prescott G Woodruff, Jerry A Krishnan, R Graham Barr, MeiLan K Han, Fernando J Martinez, Alejandro P Comellas, Allison A Lambert, Joel D Kaufman, Mark T Dransfield, J Michael Wells, Richard E Kanner, Robert Paine III, Eugene R Bleecker, Laura M Paulin, Nadia N Hansel, M Bradley Drummond
发表日期
2018/7
期刊
Annals of the American Thoracic Society
卷号
15
期号
7
页码范围
808-816
出版商
American Thoracic Society
简介
Rationale: Rural residence is associated with poor outcomes in several chronic diseases. The association between rural residence and chronic obstructive pulmonary disease (COPD) exacerbations remains unclear.
Objectives: In this work, we sought to determine the independent association between rural residence and COPD-related outcomes, including COPD exacerbations, airflow obstruction, and symptom burden.
Methods: A total of 1,684 SPIROMICS (Subpopulations and Intermediate Outcome Measures in COPD Study) participants with forced expiratory volume in 1 second/forced vital capacity < 0.70 had geocoding-defined rural-urban residence status determined (N = 204 rural and N = 1,480 urban). Univariate and multivariate logistic and negative binomial regressions were performed to assess the independent association between rurality and COPD outcomes, including exacerbations, lung function, and …
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RM Burkes, AJ Gassett, AS Ceppe, W Anderson… - Annals of the American Thoracic Society, 2018