作者
Kivanc Topuz, Ahmet Colak, Berker Cemil, Murat Kutlay, Mehmet Nusret Demircan, Hakan Simsek, Osman Ipcioglu, Zafer Kucukodaci, Gunalp Uzun
发表日期
2010/10/1
期刊
Archives of medical research
卷号
41
期号
7
页码范围
506-512
出版商
Elsevier
简介
BACKGROUND AND AIMS
We undertook this study to investigate the possible beneficial effects of combined hypothermia and hyperbaric oxygen (HBO) treatment in comparison with methylprednisolone in experimental spinal cord injury (SCI).
METHODS
Forty eight male Wistar albino rats (200–250 g) were randomized into six groups; A (normothermic control group; only laminectomy), B (normothermic trauma group; laminectomy + spinal trauma), C (normothermic methylprednisolone group; laminectomy + spinal trauma + methylprednisolone treated), D (hypothermia group; laminectomy + spinal trauma + hypothermia treated); E (HBO group; laminectomy + spinal trauma + HBO therapy), F (hypothermia and HBO group; laminectomy + spinal trauma + hypothermia and HBO treated) each containing eight rats. Neurological assessments were performed 24 h after trauma and spinal cord tissue samples had been …
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K Topuz, A Colak, B Cemil, M Kutlay, MN Demircan… - Archives of medical research, 2010