作者
Mathias Ørholt, Frederik L Aaberg, Kiya Abebe, S Walsh, Randall K Roenigk, Alessandro Venzo, Grethe Schmidt, Helle Klyver, David H Jensen, Mikkel Herly, Peter V Vester‐Glowinski
发表日期
2022/9
期刊
Journal of Surgical Oncology
卷号
126
期号
3
页码范围
555-562
简介
Background
Risk factors for local atypical fibroxanthoma (AFX) recurrence and progression to pleomorphic dermal sarcoma (PDS) have not previously been identified.
Objective
To identify risk factors and provide follow‐up suggestions for local AFX recurrence and progression to PDS.
Methods and Materials
A literature search was performed in the PubMed, EMBASE, and Cochrane databases. The PRISMA and MOOSE guidelines were followed. The risks of local AFX recurrence and progression to PDS were presented as Kaplan–Meier plots and risk factors were presented as hazard ratios (HRs) calculated with univariate and multivariate Cox regression.
Results
Five hundred and ninety‐eight patients with AFX from 14 studies were included. Age >74 years and male sex significantly increased the risk of local recurrence (HR: 7.31 [95% confidence interval [CI]: 1.78–30.0], p < 0.01 and HR: 2.89 [95% CI: 1.04 …
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M Ørholt, FL Aaberg, K Abebe, S Walsh, RK Roenigk… - Journal of Surgical Oncology, 2022