作者
Mathias Ørholt, Kiya Abebe, Louise E Rasmussen, Frederik L Aaberg, Lærke J Lindskov, Grethe Schmidt, Anne Lene Wagenblast, Michael M Petersen, Anand C Loya, Søren Daugaard, Mikkel Herly, David Hebbelstrup Jensen, Peter Vester-Glowinski
发表日期
2023/12/1
期刊
Journal of the American Academy of Dermatology
卷号
89
期号
6
页码范围
1177-1184
出版商
Mosby
简介
Background
The prognosis of patients with atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) remains uncertain and no standardized follow-up programs have been established.
Objective
To recommend a standardized follow-up programs of patients with AFX and PDS based on nationwide long-term estimates of local recurrence and metastasis.
Methods
All patients with AFX and PDS in Denmark between 2002-2022 were included. Danish National Registries were used to estimate the risks of local recurrence and metastasis for AFX and PDS.
Results
The 5-year risk of local recurrence was 10% for AFX and 17% for PDS. The 5-year risk of metastasis was 0.8% for AFX and 16% for PDS. PDS metastasized within three years in >90% of the patients with the lungs as the primary metastasis site (50%). Invasion beyond the subcutis, perineural/intravascular infiltration and increasing age significantly …
学术搜索中的文章
M Ørholt, K Abebe, LE Rasmussen, FL Aaberg… - Journal of the American Academy of Dermatology, 2023