作者
Giovanni Giulietti, Federico Giove, Girolamo Garreffa, Claudio Colonnese, Silvia Mangia, Bruno Maraviglia
发表日期
2008/8/15
期刊
NeuroImage
卷号
42
期号
2
页码范围
626-634
出版商
Academic Press
简介
Functional magnetic resonance imaging (fMRI) has emerged during the last decade as the main non-invasive technique for the investigation of human brain function. More recently, fMRI was also proposed for functional studies of the human spinal cord, but with controversial results. In fact, the functional contrast is not well-characterized, and even its origin has been challenged. In the present work, we characterized the temporal features of the functional signal evoked in the human spinal cord by a motor task, studied with an approach based on time-locked averaging of functional time series of different durations. Based on the results here reported, we defined an impulse-response function (irf) able to explain the functional response for motor tasks in the interval of 15-42 s of duration, thus suggesting the linearity of the phenomenon in this interval. Conversely, with stimulation durations ranging between 3 and 9 s, the …
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