作者
Thananya Boonyasirinant, Prabhakar Rajiah, Randolph M Setser, Michael L Lieber, Harry M Lever, Milind Y Desai, Scott D Flamm
发表日期
2009/7/14
期刊
Journal of the American College of Cardiology
卷号
54
期号
3
页码范围
255-262
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of the study was to determine if patients with hypertrophic cardiomyopathy (HCM), both with and without myocardial fibrosis, have altered aortic stiffness as assessed by magnetic resonance imaging (MRI) pulse wave velocity (PWV) measurements.
Background
Abnormal aortic stiffness implies an unfavorable prognosis and has been established in a variety of aortic diseases and ischemic cardiomyopathy. However, the relationship between aortic stiffness and HCM has not been studied previously.
Methods
The study was institutional review board approved and Health Insurance Portability and Accountability Act of 1996 compliant. Velocity-encoded MRI was performed in 100 HCM and 35 normal control subjects. PWV was determined between the mid-ascending and -descending thoracic aorta. Delayed-enhancement MRI was acquired for identification of myocardial fibrosis.
Results
Mean age was …
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