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This study investigated the prevalence of diverse Ambler class β-lactamase-encoding genes in 40 carbapenem-insensitive Acinetobacter baumannii isolates collected from two hospitals in Egypt during the period January–March 2012.

The resistance levels to different groups of antimicrobial agents were determined. PCR was used to detect the different Ambler class β-lactamases encoding the following genes: bla_TEM, bla_SHV, bla_CTX-M, bla_VEB, bla_PER, bla_GES, bla_VIM, bla_IMP, bla_SIM, bla_SPM, bla_GIM, bla_NDM, bla_ADC, bla_OXA-23, bla_OXA-24, bla_OXA-51, and bla_OXA-58. ISAba1 and int1 were detected by PCR.

The isolates were 100% resistant to amoxicillin–clavulanate, aztreonam, cefepime, cefotaxime, and ceftazidime. Of the isolates, 5% were resistant to colistin, 45% to amikacin, 70% to imipenem, and 85% to ciprofloxacin. The bla_ADC- and bla_OXA-51-like genes were detected …