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Baseline and follow-up data from 102 patients using intracorporeal (IC) injection for erectile dysfunction (ED) following RP were retrospectively collected. We compared baseline International Index for Erectile Function (IIEF) questionnaires with the abridged IIEF-5 questionnaires, referred to as the Sexual Health Inventory of Men (SHIM) to determine drug efficacy. The mean presurgery SHIM score was 21.75±5.23, which decreased to 4.23±3.48 after surgery and increased to 19.46±8.78 post-treatment. Overall, 68%(69/102) of patients achieved and maintained erections sufficient for sexual intercourse and 48%(49/102) of patients continued long-term therapy with a mean use of 3.7±1.9 y. In all, 52%(53/102) patients discontinued IC therapy. However when excluding patients who switched to oral therapy, had loss of partner or return of normal erections; the compliance to IC injections was 70.6%(71/102). There was …