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To assess whether early introduction of the Medicated Urethral System for Erection (MUSE^TM, Vivus Inc., Mountain View, CA, USA) after radical prostatectomy (RP) results in a shorter recovery time for the return to functional erections and successful sexual activity.

In a prospective study of 91 sexually active men who had a nervesparing RP for prostate cancer, 56 were treated with MUSE (125 or 250 µg three times per week for 6 months) while the remaining 35 had no erectogenic aids, except as necessary when attempting sexual activity. Selfadministration of MUSE was initiated ≈ 3 weeks after RP. Treatment efficacy was analysed by the patient’s response to the Sexual Health Inventory for Men (SHIM) questionnaire.

The mean patient age was ≈ 59 years and the median followup 6 months; the compliance rate was 68%. Patients reported a …