作者
Zongwu Cai, Yanqing Sun
发表日期
2003/3
期刊
Scandinavian Journal of Statistics
卷号
30
期号
1
页码范围
93-111
出版商
Blackwell Publishing Ltd
简介
This article develops a local partial likelihood technique to estimate the time‐dependent coefficients in Cox's regression model. The basic idea is a simple extension of the local linear fitting technique used in the scatterplot smoothing. The coefficients are estimated locally based on the partial likelihood in a window around each time point. Multiple time‐dependent covariates are incorporated in the local partial likelihood procedure. The procedure is useful as a diagnostic tool and can be used in uncovering time‐dependencies or departure from the proportional hazards model. The programming involved in the local partial likelihood estimation is relatively simple and it can be modified with few efforts from the existing programs for the proportional hazards model. The asymptotic properties of the resulting estimator are established and compared with those from the local constant fitting. A consistent estimator of the …
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