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Managing the integrity of products and processes in a multi-stakeholder supply chain environment is a significant challenge. Many current solutions suffer from data fragmentation, lack of reliable provenance, and diverse protocol regulations across multiple distributions and processes. Amongst other solutions, Blockchain has emerged as a leading technology, since it provides secure traceability and control, immutability, and trust creation among stakeholders in a low cost IT solution. Although Blockchain is making a significant impact in many areas, there are many impediments to its widespread adoption in supply chains. This article is the first survey of its kind, with detailed analysis of the challenges and future directions in Blockchain-enabled supply chains. We review the existing digitalization of the supply chain including the role of GS1 standards and technologies. Current use cases and startups in the …