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Materials and Methods:

A descriptive cross-sectional survey of adolescent girls’ parents was undertaken in two urban and two rural secondary schools in Lagos. Univariate and multivariate analysis were carried out using logistic regression to determine correlates of parental acceptance of HPV vaccine.

Results:

Of the 318 respondents, 45.9% had poor knowledge of cervical cancer and HPV infection, whereas 29.6% had good knowledge. Majority (54.7%) also had poor knowledge of HPV vaccine, whereas 26.7% had good knowledge. Most (72%) would vaccinate their daughters if vaccines were free, whereas only 35.5% would, if not free. Poor knowledge of cervical cancer and HPV infection significantly reduced the likelihood of vaccination even if free (adjusted odds ratio [OR]= 0.48; 95% confidence interval [CI]= 0.24–0.94; P= 0.0325), whereas good knowledge of HPV vaccines (adjusted OR= 6.11; 95% CI= 1.37 …