作者
Satheesh Gujarathi, Xingui Liu, Lin Song, Howard Hendrickson, Guangrong Zheng
发表日期
2014/8/26
期刊
Tetrahedron
卷号
70
期号
34
页码范围
5267-5273
出版商
Pergamon
简介
Development of an efficient synthesis of fully substituted pyrroles via a sequential propargylation/amination/cycloisomerization was accomplished using AgSbF6 as a catalyst. The one-pot three-component reaction of propargylic alcohols, 1,3-dicarbonyl compounds, and primary amines proceeds at a mild temperature, which prevents the formation of furan by-product. The reaction was also successfully applied to the more basic aliphatic amines with the addition of 1.1 equiv of acetic acid.
学术搜索中的文章
S Gujarathi, X Liu, L Song, H Hendrickson, G Zheng - Tetrahedron, 2014