作者
Francesca Collino, Francesca Rapetti, Francesco Vasques, Giorgia Maiolo, Tommaso Tonetti, Federica Romitti, Julia Niewenhuys, Tim Behnemann, Luigi Camporota, Günter Hahn, Verena Reupke, Karin Holke, Peter Herrmann, Eleonora Duscio, Francesco Cipulli, Onnen Moerer, John J Marini, Michael Quintel, Luciano Gattinoni
发表日期
2019/1/1
期刊
Anesthesiology
卷号
130
期号
1
页码范围
119-130
简介
EDITOR’S PERSPECTIVE
What We Already Know about This Topic
Positive end-expiratory pressure protects against ventilation-induced lung injury by improving homogeneity of ventilation, but positive end-expiratory pressure contributes to the mechanical power required to ventilate the lung
What This Article Tells Us That Is New
This in vivo study (36 pigs mechanically ventilated in the prone position) suggests that low levels of positive end-expiratory pressure reduce injury associated with atelectasis, and above a threshold level of power, positive end-expiratory pressure causes lung injury and adverse hemodynamics
Background
Positive end-expiratory pressure is usually considered protective against ventilation-induced lung injury by reducing atelectrauma and improving lung homogeneity. However, positive end-expiratory …
学术搜索中的文章
F Collino, F Rapetti, F Vasques, G Maiolo, T Tonetti… - Anesthesiology, 2019