作者
Marc Valentí, Isabella Pacchiarotti, Adriane R Rosa, C Mar Bonnín, Dina Popovic, Alessandra MA Nivoli, Andrea Murru, Íria Grande, Francesc Colom, Eduard Vieta
发表日期
2011/3
期刊
Bipolar disorders
卷号
13
期号
2
页码范围
145-154
出版商
Blackwell Publishing Ltd
简介
Valentí M, Pacchiarotti I, Rosa AR, Bonnín CM, Popovic D, Nivoli AMA, Murru A, Grande Í, Colom F, Vieta E. Bipolar mixed episodes and antidepressants: a cohort study of bipolar I disorder patients.
Bipolar Disord 2011: 13: 145–154. © 2011 The Authors.
Journal compilation © 2011 John Wiley & Sons A/S.
Objectives: The aim of this study was to elucidate the factors associated with the occurrence of mixed episodes, characterized by the presence of concomitant symptoms of both affective poles, during the course of illness in bipolar I disorder patients treated with an antidepressant, as well as the role of antidepressants in the course and outcome of the disorder.
Method: We enrolled a sample of 144 patients followed for up to 20 years in the referral Barcelona Bipolar Disorder Program and compared subjects who had experienced at least one mixed episode during the follow‐up (n = 60) with subjects who …
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