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Indonesia is thethirdlargestcigaretteusersafter Chinaand India, which reached 146.86 million inhabitants. Smoking behavior is engulfi ng all circles, including children. Dangers of smoking are undoubtedly makes a person not a long life. When compared with non smokers, smokers aged on average 10 years shorter and spend millions of dollars. Inhaled cigarette smoke may accelerate the decline in lung physiology caused by changes in the structure and function of the airway or parenchyma (tissue) in the lung. The objective of this study was to determine differences in pulmonary function (Vital Capacity/VC, Forced Vital Capacity/FVC, and Forced Vital Capacity of the fi rst second/FEV1) in male smokers and non smokers at the Medical Faculty of uhammadiyah