作者
Maushmi S Kumar, Tanuja T Yadav, Rohan R Khair, Godefridus J Peters, Mayur C Yergeri
发表日期
2019/9/1
来源
Current pharmaceutical design
卷号
25
期号
31
页码范围
3323-3338
出版商
Bentham Science Publishers
简介
Background
Many anticancer drugs have been developed for clinical usage till now, but the major problem is the development of drug-resistance over a period of time in the treatment of cancer. Anticancer drugs produce huge adverse effects, ultimately leading to death of the patient. Researchers have been focusing on the development of novel molecules with higher efficacy and lower toxicity; the anti-malarial drug artemisinin and its derivatives have exhibited cytotoxic effects.
Methods
We have done extensive literature search for artemisinin for its new role as anti-cancer agent for future treatment. Last two decades papers were referred for deep understanding to strengthen its role.
Result
Literature shows changes at 9, 10 position in the artemisinin structure produces anticancer activity. Artemisinin shows anticancer activity in leukemia, hepatocellular carcinoma, colorectal and breast cancer cell lines. Artemisinin …
引用总数
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