作者
Jennifer Chung, Louis-Mathieu Stevens, Maral Ouzounian, Ismail El-Hamamsy, Ismail Bouhout, Francois Dagenais, Andreanne Cartier, Mark D Peterson, Munir Boodhwani, Ming Guo, John Bozinovski, Michael H Yamashita, Carly Lodewyks, Rony Atoui, Bindu Bittira, Darrin Payne, Christopher Tarola, Michael WA Chu, Canadian Thoracic Aortic Collaborative
发表日期
2019/2/26
期刊
Circulation
卷号
139
期号
9
页码范围
1177-1184
出版商
Lippincott Williams & Wilkins
简介
Background
Contemporary outcomes after surgical management of thoracic aortic disease have improved; however, the impact of sex-related differences is poorly understood.
Methods
A total of 1653 patients (498 [30.1%] female) underwent thoracic aortic surgery with hypothermic circulatory arrest between 2002 and 2017 in 10 institutions of the Canadian Thoracic Aortic Collaborative. Outcomes of interest were in-hospital death, stroke, and a modified Society of Thoracic Surgeons–defined composite for mortality or major morbidity (stroke, renal failure, deep sternal wound infection, reoperation, prolonged ventilation). Multivariable logistic regression was used to determine independent predictors of these outcomes.
Results
Women were older (mean±SD, 66±13 years versus 61±13 years; P<0.001), with more hypertension and renal failure, but had less coronary disease, less previous cardiac surgery, and …
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J Chung, LM Stevens, M Ouzounian, I El-Hamamsy… - Circulation, 2019