作者
Troy H Puar, Chin Meng Khoo, Colin Jingxian Tan, Aaron Kian Ti Tong, Michael Chien Sheng Tan, Ada Ee Der Teo, Keng Sin Ng, Kang Min Wong, Anthonin Reilhac, Jim O’Doherty, Celso E Gomez-Sanchez, Peng Chin Kek, Szemen Yee, Alvin WK Tan, Matthew Bingfeng Chuah, Daphne Hui Min Lee, Kuo Weng Wang, Charles Qishi Zheng, Luming Shi, Edward George Robins, Roger Sik Yin Foo
发表日期
2022/6/1
期刊
Journal of Hypertension
卷号
40
期号
6
页码范围
1179-1188
出版商
LWW
简介
Objective:
Adrenal vein sampling (AVS) is recommended to subtype primary aldosteronism, but it is technically challenging. We compared 11 C-Metomidate-PET-computed tomography (PET-CT) and AVS for subtyping of primary aldosteronism.
Methods:
Patients with confirmed primary aldosteronism underwent both AVS and 11 C-Metomidate PET-CT (post-dexamethasone). All results were reviewed at a multidisciplinary meeting to decide on final subtype diagnosis. Primary outcome was accuracy of PET versus AVS to diagnosis of unilateral primary aldosteronism based on post-surgical biochemical cure. Secondary outcome was accuracy of both tests to final subtype diagnosis.
Results:
All 25 patients recruited underwent PET and successful AVS (100%). Final diagnosis was unilateral in 22 patients, bilateral in two and indeterminate in one due to discordant lateralization. Twenty patients with unilateral primary …
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TH Puar, CM Khoo, CJ Tan, AKT Tong, MCS Tan… - Journal of Hypertension, 2022