作者
Robert C Groom, Reed D Quinn, Paul Lennon, Desmond J Donegan, John H Braxton, Robert S Kramer, Paul W Weldner, Louis Russo, Seth D Blank, Angus A Christie, Andreas H Taenzer, Richard J Forest, Cantwell Clark, Janine Welch, Cathy S Ross, Gerald T O'Connor, Donald S Likosky
发表日期
2009/5
期刊
Circulation: Cardiovascular Quality and Outcomes
卷号
2
期号
3
页码范围
191-198
出版商
Lippincott Williams & Wilkins
简介
Background— Neurobehavioral impairment is a common complication of coronary bypass surgery. Cerebral microemboli during cardiopulmonary bypass (CPB) are a principal mechanism of cognitive injury. The aim of this work was to study the occurrence of cerebral embolism during CPB and to evaluate the effectiveness of evidence-based CPB circuit component and process changes on the exposure of the patient to emboli.
Methods and Results— M-Mode Doppler was used to detect emboli in the inflow and outflow of cardiopulmonary circuit and in the right and left middle cerebral arteries. Doppler signals were merged into a single display to allow real-time associations between discrete clinical techniques and emboli detection. One hundred sixty-nine isolated coronary artery bypass grafting (CABG) patients were studied between 2002 and 2008. There was no statistical difference in median microemboli …
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RC Groom, RD Quinn, P Lennon, DJ Donegan… - Circulation: Cardiovascular Quality and Outcomes, 2009