作者
Nathan R Schneider, Tianyou Xie, SE Glover, Sergei Y Tolmachev, Zhongyum Dong, Henry B Spitz
发表日期
2018/10
期刊
Journal of Radioanalytical and Nuclear Chemistry
卷号
318
页码范围
235-239
出版商
Springer International Publishing
简介
Targeted alpha therapy has the properties of direct ionization, oxygen independency, high linear energy transfer, a short half-life, and minimal depth of penetration, which are advantageous in cancer treatment. This modified, inexpensive, high-resolution, autoradiographic study of 232Th decay in a tissue specimen, to both locate and quantify individual alpha-particle origins, track lengths, and dose rates, utilized conventional Ilford Pan F Plus, 135–36, Black and White, 35 mm, ISO 50 film. Dose rates measured 0.14 cGy d−1 in the liver, 0.03 cGy d−1 in the right kidney, and 0.003 cGy d−1 in the heart, leading to a dosimetric concern of where the final alpha-particle deposition occurs.
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