作者
Erberto Carluccio, Frank Lloyd Dini, Paolo Biagioli, Rosanna Lauciello, Anca Simioniuc, Cinzia Zuchi, Gianfranco Alunni, Gianpaolo Reboldi, Mario Marzilli, Giuseppe Ambrosio
发表日期
2013/8
期刊
European journal of heart failure
卷号
15
期号
8
页码范围
868-876
简介
Aims
Although many transthoracic echocardiographic (TTE) measurements have been shown to predict outcome in heart failure (HF), whether incremental risk prediction is afforded by their combination is unknown. We developed a simple echocardiographic risk score of mortality in HF patients.
Methods and results
We performed TTE in 747 systolic HF patients followed‐up for 34 ± 23 months. The Cox hazard model was used to evaluate the association between 14 TTE parameters and death. The Echo Heart Failure Score (EHFS) was derived by assigning the value of 1 to each independent predictor when present, and 0 when it was absent, and then by summing the number. The 3‐year risk prediction improvement was tested by adding the EHFS to a model containing clinical predictors, and by calculating the C index and net reclassification improvement (NRI). Five baseline TTE variables (end‐systolic volume …
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