作者
Frank Lloyd Dini, Lauro Cortigiani, Umberto Baldini, Andrea Boni, Rossella Nuti, Luca Barsotti, Giovanni Micheli
发表日期
2002/3/1
期刊
The American journal of cardiology
卷号
89
期号
5
页码范围
518-523
出版商
Excerpta Medica
简介
Previous studies have shown that abnormal mitral flow patterns and left atrial (LA) enlargement are independently associated with survival in patients with left ventricular (LV) dysfunction. However, it is not known whether these outcome indicators can provide different information in patients of various age groups. This study was designed to assess the prognostic value of the restrictive mitral flow pattern (RMFP) and increased LA size in patients with LV dysfunction (ejection fraction <45%) grouped into those ≤70 years old (n = 102; mean age 61) and those >70 years old (n = 105; mean age 78). Echocardiographic and Doppler indexes were recorded in patients with LV systolic dysfunction due to dilated cardiomyopathy who were followed up for 22 ± 14 months. In patients >70 years, indexed LA size (>26 mm/m2) was the single best predictor of death (hazard ratio [HR] 3.0, p = 0.018) and emerged as the most …
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