作者
Vitantonio Di Bello, Enrica Talini, Giulia Dell'Omo, Cristina Giannini, Maria Grazia Delle Donne, Maria Laura Canale, Carmela Nardi, Caterina Palagi, Frank Lloyd Dini, Giuseppe Penno, Stefano Del Prato, Mario Marzilli, Roberto Pedrinelli
发表日期
2010/4/1
期刊
American journal of hypertension
卷号
23
期号
4
页码范围
405-412
出版商
Oxford University Press
简介
Background
Prehypertension predicts established hypertension. In this study, the aim was to analyze left ventricular (LV) mechanics in borderline prehypertensive (pre-HT) and hypertensive (HT) subjects through two-dimensional (2D)-strain echocardiography and then evaluate possible relations between cardiac parameters and insulin metabolism (homeostasis model assessment of insulin resistance (HOMAIR)).
Methods
Seventy-four consecutive newly diagnosed, untreated HT were divided, on the basis of their office blood pressure (BP) measurements, confirmed by ambulatory BP monitoring (ABPM), in 41 borderline pre-HT (ABPM: 122.5 ± 6.7/76.2 ± 5.2mmHg) and 33 never-treated mild HT (ABPM: 138.3 ± 7.3/87.6 ± 7.1mmHg). Thirty-three healthy normotensive (NT) controls (ABPM: 114.8 ± 6.3/73.1 ± 6.1mmHg) (P < 0.0001) were also studied (NT). All subjects performed …
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VD Bello, E Talini, G Dell'Omo, C Giannini… - American journal of hypertension, 2010