作者
Fuat Bilgili, Halil Ibrahim Balci, Kayahan Karaytug, Kerim Sariyilmaz, Ata Can Atalar, Ergun Bozdag, Meral Tuna, Bilge Bilgic, Nezahat Gurler
发表日期
2015/10
期刊
Clinical Orthopaedics and Related Research®
卷号
473
页码范围
3190-3196
出版商
Springer US
简介
Background
Infection after open fractures is a common complication. Treatment options for infections developed after intramedullary nailing surgery remain a topic of controversy. We therefore used a rat fracture model to evaluate the effects of infection on osseous union when the implant was maintained.
Questions/purposes
In a rat model, (1) does infection alter callus strength; (2) does infection alter the radiographic appearance of callus; and (3) does infection alter the histological properties of callus?
Methods
An open femoral fracture was created and fixed with an intramedullary Kirschner wire in 72 adult male Sprague-Dawley rats, which were divided into two study groups. In the infection group, the fracture site was contaminated with Staphylococcus aureus (36 animals), whereas in the control group, there was no …
学术搜索中的文章
F Bilgili, HI Balci, K Karaytug, K Sariyilmaz, AC Atalar… - Clinical Orthopaedics and Related Research®, 2015