作者
Michel Azizi, Roland E Schmieder, Felix Mahfoud, Michael A Weber, Joost Daemen, Justin Davies, Jan Basile, Ajay J Kirtane, Yale Wang, Melvin D Lobo, Manish Saxena, Lida Feyz, Florian Rader, Philipp Lurz, Jeremy Sayer, Marc Sapoval, Terry Levy, Kintur Sanghvi, Josephine Abraham, Andrew SP Sharp, Naomi DL Fisher, Michael J Bloch, Helen Reeve-Stoffer, Leslie Coleman, Christopher Mullin, Laura Mauri, Desmond Jay, Nedaa Skeik, Robert Schwartz, Suhail Dohad, Ronald Victor, Josh Costello, Courtney Walsh, Theophilus Owan, Anu Abraham, Piotr Sobieszczky, Jonathan Williams, Michael J Bloch, Chanwit Roongsritong, Thomas Todoran, Eric Powers, Emily Hodskins, Pete Fong, Cheryl Laffer, James Gainer, Mark Robbins, John P Reilly, Michael Cash, Jessie Goldman, Sandeep Aggarwal, Gary Ledley, David Hsi, Scott Martin, Edward Portnay, David Calhoun, Thomas McElderry, William Maddox, Suzanne Oparil, Pei-Hsiu Huang, Powell Jose, Matheen Khuddus, Suzanne Zentko, James O'Meara, Ilie Barb, Joseph Garasic, Doug Drachman, Randy Zusman, Kenneth Rosenfield, Chandan Devireddy, Janice Lea, Bryan Wells, Rick Stouffer, Alan Hinderliter, Eric Pauley, Srinivasa Potluri, Scott Biedermann, Sripal Bangalore, Stephen Williams, David Zidar, Mehdi Shishehbor, Barry Effron, Marco Costa, Ajay J Kirtane, Jai Radhakrishnan, Melvin D Lobo, Anthony Mathur, Ajay Jain, Sudha Ganesh Iyer, Nicholas Robinson, Sadat Ali Edroos, Amit Patel, David Beckett, Clare Bent, Neil Chapman, Matthew Shun-Shin, James Howard, Anil Joseph, Richard D'Souza, Robert Gerber, Mohamad Faris, Andrew J Marshall, Cristina Elorz, Robert Höllriegel, Karl Fengler, Karl-Philipp Rommel, Michael Böhm, Sebastian Ewen, Jelena Lucic, Roland E Schmieder, Christian Ott, Axel Schmid, Michael Uder, L Christian Rump, Johannes Stegbauer, Patric Kröpil, Erika Cornu, David Fouassier, Philippe Gosse, Antoine Cremer, Hervé Trillaud, Panteleimon Papadopoulos, Atul Pathak, Benjamin Honton, Pierre Lantelme, Constance Berge, Pierre-Yves Courand, Peter J Blankestijn, Michiel Voskuil, Zwaantina Rittersma, AA Kroon, WH van Zwam, Alexandre Persu, Jean Renkin
发表日期
2018/6/9
期刊
The Lancet
卷号
391
期号
10137
页码范围
2335-2345
出版商
Elsevier
简介
Background
Early studies suggest that radiofrequency-based renal denervation reduces blood pressure in patients with moderate hypertension. We investigated whether an alternative technology using endovascular ultrasound renal denervation reduces ambulatory blood pressure in patients with hypertension in the absence of antihypertensive medications.
Methods
RADIANCE-HTN SOLO was a multicentre, international, single-blind, randomised, sham-controlled trial done at 21 centres in the USA and 18 in Europe. Patients with combined systolic–diastolic hypertension aged 18–75 years were eligible if they had ambulatory blood pressure greater than or equal to 135/85 mm Hg and less than 170/105 mm Hg after a 4-week discontinuation of up to two antihypertensive medications and had suitable renal artery anatomy. Patients were randomised (1:1) to undergo renal denervation with the Paradise system …
学术搜索中的文章
M Azizi, RE Schmieder, F Mahfoud, MA Weber… - The Lancet, 2018