作者
Jerry Avorn, Mark Monane, Jerry H Gurwitz, Robert J Glynn, Igor Choodnovskiy, Lewis A Lipsitz
发表日期
1994/3/9
期刊
Jama
卷号
271
期号
10
页码范围
751-754
出版商
American Medical Association
简介
Objective
—To determine the effect of regular intake of cranberry juice beverage on bacteriuria and pyuria in elderly women.
Design
—Randomized, double-blind, placebo-controlled trial.
Subjects
—Volunteer sample of 153 elderly women (mean age, 78.5 years).
Intervention
—Subjects were randomly assigned to consume 300 mL per day of a commercially available standard cranberry beverage or a specially prepared synthetic placebo drink that was indistinguishable in taste, appearance, and vitamin C content but lacked cranberry content.
Outcome Measures
—A baseline urine sample and six clean-voided study urine samples were collected at approximately 1-month intervals and tested quantitatively for bacteriuria and the presence of white blood cells.
Results
—Subjects randomized to the cranberry beverage had odds of bacteriuria (defined as organisms numbering ≥105/mL) with pyuria that were only 42% of …
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