作者
Wei Zheng, Dale F McLerran, Betsy Rolland, Xianglan Zhang, Manami Inoue, Keitaro Matsuo, Jiang He, Prakash Chandra Gupta, Kunnambath Ramadas, Shoichiro Tsugane, Fujiko Irie, Akiko Tamakoshi, Yu-Tang Gao, Renwei Wang, Xiao-Ou Shu, Ichiro Tsuji, Shinichi Kuriyama, Hideo Tanaka, Hiroshi Satoh, Chien-Jen Chen, Jian-Min Yuan, Keun-Young Yoo, Habibul Ahsan, Wen-Harn Pan, Dongfeng Gu, Mangesh Suryakant Pednekar, Catherine Sauvaget, Shizuka Sasazuki, Toshimi Sairenchi, Gong Yang, Yong-Bing Xiang, Masato Nagai, Takeshi Suzuki, Yoshikazu Nishino, San-Lin You, Woon-Puay Koh, Sue K Park, Yu Chen, Chen-Yang Shen, Mark Thornquist, Ziding Feng, Daehee Kang, Paolo Boffetta, John D Potter
发表日期
2011/2/24
期刊
New England Journal of Medicine
卷号
364
期号
8
页码范围
719-729
出版商
Massachusetts Medical Society
简介
Background
Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin.
Methods
We performed pooled analyses to evaluate the association between BMI and the risk of death among more than 1.1 million persons recruited in 19 cohorts in Asia. The analyses included approximately 120,700 deaths that occurred during a mean follow-up period of 9.2 years. Cox regression models were used to adjust for confounding factors.
Results
In the cohorts of East Asians, including Chinese, Japanese, and Koreans, the lowest risk of death was seen among persons with a BMI (the weight in kilograms divided by the square of the height in meters) in the range of 22.6 to 27.5. The risk was elevated among persons with BMI levels either higher or lower than that range — by a factor of …
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