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Australian, Iranian and Portuguese university students (n = 967) completed the University Students Depression Inventory (USDI) in English, Persian and Portuguese languages, respectively. A series of MANOVA analyses were used to examine differences in depression symptoms as an effect of the country and demographic variables. Interactions were also examined. The results indicated that country, gender and year level had some impact on the depressive symptoms of the university students. Australian students were more depressed than the Iranian and Portuguese students, while Iranian students were more depressed than the Portuguese students. Sub-scales of USDI – Lethargy, Motivation and Cognitive/Emotional – were also used to compare the depressive symptoms of students. The Australian female students reported a significantly higher level of lethargy than their male counterparts. Similarly, the first …