作者
Xibiao Ye, Frank H Pierik, Jürgen Angerer, Helle Margrete Meltzer, Vincent WV Jaddoe, Henning Tiemeier, Jane A Hoppin, Matthew P Longnecker
发表日期
2009/9/1
期刊
International journal of hygiene and environmental health
卷号
212
期号
5
页码范围
481-491
出版商
Urban & Fischer
简介
Concerns about reproductive and developmental health risks of exposure to organophosphate (OP) pesticides, phthalates, and bisphenol A (BPA) among the general population are increasing. Six dialkyl phosphate (DAP) metabolites, 3,5,6-trichloro-2-pyridinol (TCPy), BPA, and fourteen phthalate metabolites were measured in 10 pooled urine samples representing 110 pregnant women who participated in the Norwegian Mother and Child Birth Cohort (MoBa) study in 2004. Daily intakes were estimated from urinary data and compared with reference doses (RfDs) and daily tolerable intakes (TDIs). The MoBa women had a higher mean BPA concentration (4.50μg/L) than the pregnant women in the Generation R Study (Generation R) in the Netherlands and the National Health and Nutrition Examination Survey (NHANES) in the United States. The mean concentration of total DAP metabolites (24.20μg/L) in MoBa …
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