作者
Krishnan Bhaskaran, Christopher T Rentsch, Brian MacKenna, Anna Schultze, Amir Mehrkar, Chris J Bates, Rosalind M Eggo, Caroline E Morton, Sebastian CJ Bacon, Peter Inglesby, Ian J Douglas, Alex J Walker, Helen I McDonald, Jonathan Cockburn, Elizabeth J Williamson, David Evans, Harriet J Forbes, Helen J Curtis, William J Hulme, John Parry, Frank Hester, Sam Harper, Stephen JW Evans, Liam Smeeth, Ben Goldacre
发表日期
2021/1/1
期刊
The lancet HIV
卷号
8
期号
1
页码范围
e24-e32
出版商
Elsevier
简介
Background
Whether HIV infection is associated with risk of death due to COVID-19 is unclear. We aimed to investigate this association in a large-scale population-based study in England.
Methods
We did a retrospective cohort study. Working on behalf of NHS England, we used the OpenSAFELY platform to analyse routinely collected electronic primary care data linked to national death registrations. We included all adults (aged ≥18 years) alive and in follow-up on Feb 1, 2020, and with at least 1 year of continuous registration with a general practitioner before this date. People with a primary care record for HIV infection were compared with people without HIV. The outcome was COVID-19 death, defined as the presence of International Classification of Diseases 10 codes U07.1 or U07.2 anywhere on the death certificate. Cox regression models were used to estimate the association between HIV infection and …
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K Bhaskaran, CT Rentsch, B MacKenna, A Schultze… - The lancet HIV, 2021