作者
Ximena Terra, Teresa Auguet, Esther Guiu-Jurado, Alba Berlanga, Josep Maria Orellana-Gavaldà, Mercè Hernández, Fàtima Sabench, Jose Antonio Porras, Jordi Llutart, Salomé Martinez, Carmen Aguilar, Daniel Del Castillo, Cristóbal Richart
发表日期
2013/11
期刊
Obesity surgery
卷号
23
页码范围
1790-1798
出版商
Springer US
简介
Background
Different studies have evaluated changes in adipo/cytokine levels after bariatric surgery and have given conflicting results. The adipo/cytokines, leptin and chemerin, and the orexigenic hormone, ghrelin, have been shown to play a role in the regulation of metabolism and appetite. The aims of our study were to test the levels of these molecules after bariatric surgery and to compare the results between Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy.
Methods
We analysed circulating levels of chemerin, ghrelin and leptin in 30 morbidly obese women (body mass index of >40 kg/m2). Subjects were studied at three time points: baseline (before the surgery started), and after 6 and 12 months.
Results
After surgery, chemerin (baseline, 95.03 ± 23.79; after 12 months, 76.80 ± 21.51; p = 0.034 …
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