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Cerebrovascular disease refers to the spectrum of brain diseases caused by impaired vasculature and blood supply. This encompasses a host of pathologic conditions such as stroke, hemorrhage, and other entities associated with vascular narrowing, obstruction, rupture, and inflammation. Vascular disease can involve large and/or small vessels. Although brain disease related to large vessel pathologic condition often manifests with significant abnormalities such as large areas of cerebral infarction or hemorrhage that can be detected with computed tomography (CT), small vessel disease (SVD) may be subtle and more