作者
N Joop Ouborg, Cino Pertoldi, Volker Loeschcke, R Kuke Bijlsma, Phil W Hedrick
发表日期
2010/4/1
来源
Trends in genetics
卷号
26
期号
4
页码范围
177-187
出版商
Elsevier
简介
Over the past twenty years conservation genetics has progressed from being mainly a theory-based field of population biology to a full-grown empirical discipline. Technological developments in molecular genetics have led to extensive use of neutral molecular markers such as microsatellites in conservation biology. This has allowed assessment of the impact of genetic drift on genetic variation, of the level of inbreeding within populations, and of the amount of gene flow between or within populations. Recent developments in genomic techniques, including next generation sequencing, whole genome scans and gene-expression pattern analysis, have made it possible to step up from a limited number of neutral markers to genome-wide estimates of functional genetic variation. Here, we focus on how the transition of conservation genetics to conservation genomics leads to insights into the dynamics of selectively …
引用总数
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学术搜索中的文章
NJ Ouborg, C Pertoldi, V Loeschcke, RK Bijlsma… - Trends in genetics, 2010